Explore Metabolism 5.0

Human metabolism, made interactive.

Run a dynamic biochemical simulation, follow pathway activity in real time, and investigate how cellular conditions reshape metabolism.

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Real-time simulation Interactive pathway tools Guided learning
Metabolism 5.0 displaying live metabolite concentrations and simulation controls

A guided tour

See the system respond as a connected whole

Metabolism 5.0 moves beyond static pathway diagrams. Concentrations, reaction rates, fluxes, and cellular conditions update together, giving users a clearer view of how biochemical systems influence one another over time.

01 · Simulation

Control the cellular environment

Run repeatable experiments and watch metabolic behavior change in response to new demands, substrates, and reaction conditions.

Core Simulation

Real-Time Metabolic Simulation

Run a continuously updating model of interconnected metabolic reactions and watch metabolite concentrations respond as the simulated cell changes.

  • Live concentration updates
  • Interconnected pathway behavior
  • Adjustable simulation speed and controls
Metabolism 5.0 real-time simulation with changing metabolite concentration graphs
Experiment

Timed Velocity Changes

Schedule changes to reaction velocities at specific simulation times to model interventions, physiological events, or changing enzyme activity.

  • Time-based reaction changes
  • Repeatable experimental setups
  • Before-and-after response analysis
Timed Velocity Changes interface for scheduled reaction adjustments

02 · Visualization & Analysis

Inspect metabolism from multiple perspectives

Move between individual metabolites, pathway-level flow, live graphs, and diagnostic data without losing sight of the larger system.

Explore

Interactive Metabolite Explorer

Select individual metabolites to examine their concentrations, production and consumption pathways, associated reactions, and changing behavior during a simulation.

  • Metabolite-specific details
  • Production and consumption tracking
  • Reaction and enzyme relationships
Metabolite Explorer showing ATP production, consumption, and reaction information
Visualize

Live Reaction Flow Map

Follow metabolic activity across pathways through a visual map that updates reaction direction and relative flux as conditions change.

  • Dynamic pathway activity
  • Reaction direction and relative flux
  • Connected pathway overview
Reaction Flow Map showing glycolysis, respiration, the TCA cycle, and oxidative phosphorylation
Analyze

Diagnostics and Flux Analysis

Inspect reaction rates, pathway fluxes, balance checks, and system-wide diagnostics for a deeper look at how the simulation is behaving.

  • Reaction-rate inspection
  • Metabolic flux analysis
  • Conservation and diagnostic checks
Diagnostics and metabolic flux analysis interface

03 · Education

Turn observation into understanding

Structured activities connect visible simulation changes to the biological principles behind them.

Learn

Guided Educational Exercises

Use structured exercises, condition presets, prompts, and live readouts to investigate how metabolic systems respond to experimentally controlled changes.

  • Scenario-based learning
  • Preset physiological conditions
  • Live observations and prompts
Guided exercise interface with presets, live readouts, and educational prompts

04 · Supporting Tools

Built for continued exploration

Supporting capabilities make the software easier to configure, interpret, maintain, and improve.

01

Adjustable Biological Conditions

Change oxygen availability, substrate supply, energy demand, and other modeled conditions to compare metabolic responses.

02

Live Concentration Graphs

Track selected metabolites over time and connect visible trends to the reactions and conditions driving them.

03

Automatic Updates

Receive new versions through the built-in update system as simulation behavior, educational content, and interface tools improve.

04

Integrated Release Notes

Review changes, fixes, and additions from within the software so each update is easy to understand.

05

Bug Reporting

Submit feedback and software issues through a dedicated reporting workflow that supports continued testing and refinement.

06

Multiple Ways to Explore

Use the software for classroom demonstrations, guided study, independent experimentation, or detailed pathway inspection.

Ready to explore?

See human metabolism in motion.

Download Metabolism 5.0 and begin investigating cellular metabolism through interactive simulation, visualization, and guided experimentation.

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